Consist of Seminary catalogues for 1828-1875 (with gaps). The earlier catalogues list the names of students and their home addresses, as well as the names of faculty and trustees. Later catalogues contain additional information about the school's educational principles, curriculum, academic calendar, and fees. The 1839 catalogue contains an historical article on the school and an announcement of Zilpah P. Grant's retirement from the Seminary. It lists the names of all the pupils that completed the course of study under Grant and Mary Lyon at Ipswich as well as at Adams Female Academy in Derry, New Hampshire. Also listed are the occupation, marital status, and place of residence of each student as of 1839.

Circulars and announcements consist chiefly of publicity pamphlets discussing the importance of instructing females and the role of the Seminary in female education and religious instruction. An article entitled "Benefits of Female Education," thought to be written by Zilpah P. Grant, discusses the importance of female education to society and how the lack of finances is a great impediment to this cause. The pamphlets urge friends and patrons to donate funds to support educating young women. Also included in the series is a newspaper notice, probably from the 1830s, announcing the commencement of winter term at the Seminary.

The administrative documents consist of reports of the 1836 and 1837 winter terms, statistics relating to students and alumnae, and a note to the trustees. The reports give the number of students and teachers at the institution and discuss the entrance requirements, course of study, and curriculum. They comment on the subjects studied such as geography, arithmetic, English grammar, chemistry, human physiology, vocal music, religion, and calisthenics. The reports also mention a "society for correspondence and for gaining and communicating general information" at the Seminary, and discuss the mental and moral culture at the school, in addition to the boarding responsibilities of the young women. Statistics in this series were probably recorded by Eunice Caldwell Cowles and they list the names, marital status, and occupations as of 1839 of all the pupils that had completed the course of study under Zilpah P. Grant and Mary Lyon at Ipswich as well as at Adams Female Academy in Derry, New Hampshire. Also included is a note written by Grant to the trustees in 1828 certifying that five students are entitled to diplomas.

This series contains the Constitution and Rules of Regulation of the Society, which was established to assist students at the Seminary in their pursuit of education and Christian benevolence. There is a list of its subscribers and benefactors, as well as abstracts of letters written to the organization by student beneficiaries pertaining to their activities after leaving the Seminary. Also included are financial notes and historical information including the number of beneficiaries and total amount dispensed by the Society.

Regulatory documents include published and unpublished rules and regulations for the conduct of students and teachers at the Seminary. There are directives pertaining to teacher relations and interactions with students, as well as "Memoranda" intended to assist teachers in regulating and supervising students. Also included are several self-assessment notes by the students reporting their adherence to the school rules and regulations.

Course records consist of a chronological chart prepared by student Ellen Odrione in 1827-1828. The chart illustrates the Biblical history of the world from Creation to Canaan.

Correspondence consists of letters written by and to Seminary students, alumnae, and teachers. The letters describe students' impressions upon arriving at the Seminary, the accommodations, daily schedule, and customs, as well as the characters of Zilpah P. Grant and Mary Lyon. One student describes her journey to the Seminary from Ohio. The correspondence of Eliza J. Snow for 1863-1864 mentions her student allowance and an outbreak of smallpox in New England. Several of the letters document the lives of alumnae missionaries and teachers. A letter by Eunice Strong (March, 1849) describes Mary Lyon's death and her thoughts about Lyon's contribution to female education. Also of note are three letters by Maria Cowles, one written while she was a student at Buckland Female School in 1829, in which she describes the accommodations, studies, government, and religion at that institution under Mary Lyon. She also describes Lyon as a teacher and mentor. The other two letters written in 1831 discuss her life as a teacher at Ipswich, the number and ages of the students, the curriculum and religious life at the school, and the Seminary's commitment to training female teachers. She also mentions her health and the method of instruction she employs in her vocal music and composition classes.

The series consists of two copies of a published address entitled "Hints on Reading" that was delivered at the Seminary by the Reverend Daniel Dana on January 15, 1834. In the address Dana advises his audience on the importance and principles of reading and provides a selection of books, including the Bible and works by Milton, the Earl of Chatham (i.e., William Pitt), Daniel Webster, and Hannah More.

Ceremonial records include the 1836 and 1838 winter term "Farewell Songs" and the 1866 and 1867 "Order of Exercises" programs of the Seminary. The programs contain the schedule for examinations and music recitations as well as the graduating ceremony program, a list of students receiving diplomas, and the senior class farewell song. Also included is the diploma for Emily Abbott, an 1833 graduate of the Seminary.

The book entitled "School Days of Beulah Romney" was written by Julia A. Eastman, who is believed to have attended the Seminary. It was published in 1872. The book is a fictionalized account of life at the Seminary, probably based on the life of Eunice Caldwell Cowles.

Historical information includes historical sketches, notes, a speech, and an article. The materials concern the founding of the Seminary and its role in advancing female education in the United States. A semi-fictional narrative published in the journal "The Massachusetts Teacher" in 1850 depicts the teaching career of an typical Ipswich graduate after leaving the Seminary. An article entitled "Ipswich Female Seminary: An Educational Experience" published in v.120 (1984) of "Essex Institute Historical Collections" gives a thorough account of the history and significance of the school. Also included are copies of articles discussing Mary Lyon, Zilpah P. Grant (later Banister), and Eunice Caldwell Cowles.

Photographs consist of a portrait of Ipswich students Elizabeth Livermore, Sadie Ross, and "Miss Trimball," as well as a stereoscopic photograph of the Seminary building. The photographs appear to date from the 1860s.